High sensitivity system for size and molecular weight measurements of proteins and bio-molecules

Avid Nano’s W130i is a high sensitivity dynamic light scattering system for size and molecular weight measurement of proteins, bio-molecules and sub-micron particles. The W130i combines unbeatable measurement performance with an economical benchtop footprint, rugged durability and supreme user convenience. It’s extraordinarily compact dimensions are the result of miniaturized ‘diamond geometry’ S.A.B.Re fibre optic technology.

Dynamic light scattering (DLS) is a well established, non-invasive technique for measuring size and size distribution of molecules and nano-materials in the 0.3 – 1000 nm size range. Dynamic light scattering is also known as photon correlation spectroscopy (PCS) and sometimes quasi-elastic light scattering (QELS). The most common application for dynamic light scattering is to measure the size of molecules or particles which are dissolved or dispersed in some kind of liquid medium. To make a dynamic light scattering measurement, a focused laser light beam is used to illuminate the liquid sample and the time dependent, scattered light intensity fluctuations are recorded and correlated. The average particle size present in the sample is directly related to the rate of change of scattered light intensity and is calculated using the Stokes-Einstein relationship.